what happened to sb能用于表达身体问题吗？

appen to sb 是固定搭配，其意为“某事（多指不好的事）发生在某人身上”。又如：
I dread to think what has happened to him. 我害怕去想他出了什么事。
Nobody will ever know what happened to her. 谁都不会知道她出了什么事。
He is truly outraged about what’s happened to him. 这一遭遇实在让他满腔愤慨。
She fell to brooding about what had happened to her. 她开始沉思默想自己的遭遇。
Nobody really minded much about what happened to them. 没人真正在意他们的遭遇。
Did you hear what happened to Jamie last night? 你听说昨天晚上杰米出什么事了吗？
If anything should happen to me, please give this letter to my wife. 万一我有什么不测，请把这封信交给我妻子。
其中的 sb 有时也可以换成 sth。如：
The puzzle remains of what happened to the ship. 那艘船发生了什么事还是个谜。
The money vanished into thin air. Nobody knows what happened to it. 钱不翼而飞，谁也不知道是怎么回事。
I don’t know what’s happened to her playing. She seems to have lost her touch. 我不知道她是怎么搞的，她好像已经失去了表演能力。