Introduction
Reconstruction of the human bladder is still one of thegreat surgical challenges in adult and pediatric urology.Different materials and techniques have been experimentallyand clinically described, with most of theseusing segments of gastro-intestinal tract. However, theuse of bowel is associated with significant morbidityand functional alteration . Alloplastic biomaterials and different operative procedures, such as autoaugmentation, have been proposed to preservethe transitional urothelium, with discouraging or notsatisfying results.
The ideal procedure for bladder augmentationshould be easy to perform without bowel and peritonealcavity violation and should guarantee good functionalresults at long-term follow-up . In the last decade, Kropp and his research group from Indianapolisevaluated the use of small intestinal submucosa (SIS), harvested from the submucosal layer of porcine intestine, as a possible bladder augmentation material,
acting as a bioscaffold for tissue regeneration in vivo in a series of experimental models in rats and dogs . Their SIS-regenerated bladder demonstrated good compliance and capacity achievement, with contractile activity and radiological and histological results similar to native bladder.
不要机器翻译的，谢谢！！希望有能人可以人工翻译个！！
介绍了人类膀胱重建仍然是一个在成人和儿童urology.Different材料和技术thegreat手术挑战一直experimentallyand临床描述，对胃肠道theseusing段最多。然而，肠theuse是与重大morbidityand功能的改变。异质的生物材料和不同手术程序，如autoaugmentation，已经被提出来preservethe结果与沮丧，notsatisfying过渡尿路上皮。对于理想的程序augmentationshould膀胱容易在没有任何肠和peritonealcavity的侵犯，应保证良好的functionalresults在长期随访。在过去的十年中，克罗普和他的研究组的小肠黏膜下层（SIS）的收获从猪体内肠道膀胱扩大术作为一种可能的材料，作为组织再生bioscaffold行事黏膜层一个系列，使用Indianapolisevaluated在大鼠和狗的实验模型。他们SIS的再生膀胱显示良好的合规和收缩活动和放射性和组织学结果类似原始膀胱容量的成就。
Introduction
Reconstruction of the human bladder is still one of thegreat surgical challenges in adult and pediatric urology.Different materials and techniques have been experimentallyand clinically described, with most of theseusing segments of gastro-intestinal tract. However, theuse of bowel is associated with significant morbidityand functional alteration . Alloplastic biomaterials and different operative procedures, such as autoaugmentation, have been proposed to preservethe transitional urothelium, with discouraging or notsatisfying results.
The ideal procedure for bladder augmentationshould be easy to perform without bowel and peritonealcavity violation and should guarantee good functionalresults at long-term follow-up . In the last decade, Kropp and his research group from Indianapolisevaluated the use of small intestinal submucosa (SIS), harvested from the submucosal layer of porcine intestine, as a possible bladder augmentation material,
acting as a bioscaffold for tissue regeneration in vivo in a series of experimental models in rats and dogs . Their SIS-regenerated bladder demonstrated good compliance and capacity achievement, with contractile activity and radiological and histological results similar to native bladder 简介
人类膀胱重建仍是 thegreat 外科手术的挑战之一在成人和儿童泌尿外科。不同的材料和技术已经临床描述的情况下，大部分的胃肠道 theseusing 段的 experimentallyand。然而，重要的 morbidityand 功能变化与相关肠的使用。异体生物材料和不同的手术过程，如 autoaugmentation，已建议对秸过渡肌层，劝阻或 notsatisfying 的结果。
膀胱 augmentationshould 的理想程序很容易执行，而肠和 peritonealcavity 的违反，应能保证良好的职能部门在长期的后续行动。在过去十年，克罗普和他的研究小组从小肠黏膜下层 (SIS) 使用 Indianapolisevaluated，收获从猪肠内的黏膜层作为一种可能的膀胱增强材料，
作为 bioscaffold 的一系列实验模型对大鼠和犬体内组织再生。他们 SIS 再生的膀胱收缩活动与影像输出结果类似于本机膀胱表现出好的法规遵从性和容量的成就，
人类的膀胱重建外科手术仍是浓厚的成人、儿童泌尿外科的挑战。不同的材料和技术已经experimentallyand临床上描述,其中大部分 theseusing胃肠道的片段。然而,使用的morbidityand肠功能相关的明显改变。Alloplastic生物材料和不同的手术方式,如 autoaugmentation,提出了保持和令人沮丧的过渡尿道上皮,或notsatisfying结果。
理想的程序是很容易的augmentationshould履行膀胱和肠道及peritonealcavity不应保证良好的 functionalresults违反在长期随访。在过去十年中,安·克洛普和他的研究小组的使用从Indianapolisevaluated小肠结膜(SIS),收获从猪小肠黏膜下层,是一个可能的膀胱术资料,
作为bioscaffold让组织再生的体内一系列的实验大鼠动物模型和狗。他们表现出良好的依从性和SIS-regenerated膀胱容量的成就,应与收缩活动及放射学及组织学结果类似于本土的膀胱。本回答被网友采纳
