"你怎么了"用英语怎么说?

可以用What happened to you ; What's come over you ; What's the matter with you ; What's wrong with you；What did you do等。

双语例句：

1、你怎么了？--没啥，有点头疼。

What's the matter with you?--Just a bit of a headache; nothing serious.

2、你怎么了？你为什么哭丧着脸？

What's wrong? Why do you wear a long face?

3、嘿，哥们儿，你怎么了？

Hi, buddy. What's wrong with you?

4、你怎么了，一整天都病（病）殃殃的？

What's the matter? You look tired and sick the whole time.

5、你怎么了？换新洗发水了？

What's going on with you? You switch shampoos or something?

6、你怎么了？不舒服吗？

What happened to you? Were you sick?

7、你怎么了，加入了什么教会吗？

What did you do, join a cult?